109425-51-6

  • Product Name:N-Fmoc-N'-trityl-L-histidine
  • Molecular Formula:C40H33N3O4
  • Purity:99%
  • Molecular Weight:619.72
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Product Details;

CAS#: 109425-51-6

Molecular Formula: C40H33N3O4

Appearance: White crystalline powder

Chinese Manufacturer Supply Top Purity 109425-51-6 with Safe Transportation

  • Molecular Formula:C40H33N3O4
  • Molecular Weight:619.72
  • Appearance/Colour:White crystalline powder 
  • Vapor Pressure:7.59E-28mmHg at 25°C 
  • Melting Point:150-155 °C 
  • Refractive Index:97 ° (C=5, CHCl3) 
  • Boiling Point:811.7 °C at 760 mmHg 
  • PKA:3.06±0.10(Predicted) 
  • Flash Point:444.7 °C 
  • PSA:93.45000 
  • Density:1.24 g/cm3 
  • LogP:7.64860 

N-Fmoc-N'-trityl-L-histidine(Cas 109425-51-6) Usage

General Description

The product number for this product was previously 04-12-1065.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

InChI:InChI=1/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-41-27-43(31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/p-1/t37-/m0/s1

109425-51-6 Relevant articles

Preparation method of N - 9 - fluorenylmethoxycarbonyl - N ' - trityl - L - histidine

-

Paragraph 0012; 0028; 0030-0032; 0034-0035, (2021/09/21)

The invention relates to the technical f...

DIPHENYLMETHANE COMPOUND

-

, (2010/10/19)

Compounds having a diphenylmethane skele...

Efficient procedure for the preparation of oligomer-free N-fmoc amino acids

Nowshuddin, Shaik,Rao,Reddy, A. Ram

experimental part, p. 2022 - 2031 (2009/11/30)

A two-step method is presented for the p...

GLP-2 compounds, formulations, and uses thereof

-

, (2008/06/13)

The present invention relates to novel h...

109425-51-6 Process route

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

2-amino-3-(N-tritylimidazolyl)propionic acid
35146-32-8,199119-46-5

2-amino-3-(N-tritylimidazolyl)propionic acid

Fmoc-His(Trt)-OH
109425-51-6

Fmoc-His(Trt)-OH

Conditions
Conditions Yield
With sodium hydrogencarbonate; In water; ethyl acetate; at 20 ℃; for 12h; pH=7 - 8;
87.22%
2-amino-3-(N-tritylimidazolyl)propionic acid; With N-cyclohexyl-cyclohexanamine; In acetone; at 20 ℃;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium carbonate; In water; acetonitrile; at 0 - 20 ℃; pH=8;
With potassium hydrogensulfate; In water; acetonitrile; pH=2 - 3;
56%
(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

2-amino-3-(N-tritylimidazolyl)propionic acid
35146-32-8,199119-46-5

2-amino-3-(N-tritylimidazolyl)propionic acid

Fmoc-His(Trt)-OH
109425-51-6

Fmoc-His(Trt)-OH

Conditions
Conditions Yield
With sodium carbonate; In 1,4-dioxane; 1.) 1h, 0 deg C, 2.) 12h, room temperature;
73%

109425-51-6 Upstream products

  • 28920-43-6
    28920-43-6

    (fluorenylmethoxy)carbonyl chloride

  • 35146-32-8
    35146-32-8

    2-amino-3-(N-tritylimidazolyl)propionic acid

  • 82911-69-1
    82911-69-1

    N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

109425-51-6 Downstream products

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    170797-85-0

    [(S)-1-[2-(tert-Butyl-dimethyl-silanyloxy)-1,1-bis-(tert-butyl-dimethyl-silanyloxymethyl)-ethylcarbamoyl]-2-(1-trityl-1H-imidazol-4-yl)-ethyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

  • 121377-67-1
    121377-67-1

    L-His-L-Leu-L-Asp-L-Ile-L-Ile-L-Trp

  • 192389-07-4
    192389-07-4

    Fmoc-Tyr(t-Bu)-Ile-His(Trt)-Pro-Phe-OH

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