87512-31-0
- Product Name:FMOC-ALA-ALA-OH
- Molecular Formula:C21H22N2O5
- Purity:99%
- Molecular Weight:382.416
Product Details;
CAS#: 87512-31-0
Molecular Formula: C21H22N2O5
Reputable Manufacturer Supply 87512-31-0 with Cheapest Price, Buy High Quality Fmoc-Ala-Ala-OH
- Molecular Formula:C21H22N2O5
- Molecular Weight:382.416
- Melting Point:175-179℃ (ethyl acetate hexane )
- Boiling Point:674.2±45.0 °C(Predicted)
- PKA:3.49±0.10(Predicted)
- PSA:104.73000
- Density:1.280±0.06 g/cm3(Predicted)
- LogP:3.28470
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87512-31-0 Process route
- 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
- 87512-31-0
(S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)propanamido)propanoic acid
Conditions | Yield |
---|---|
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2.73333h;
With piperidine; In N,N-dimethyl-formamide; at 20 ℃;
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Further stages;
|
78% |
Multi-step reaction with 2 steps
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h
2: trifluoroacetic acid / chloroform / 7 h
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; chloroform;
|
|
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide / dichloromethane / 6 h / 5 °C
2: sodium hydrogencarbonate / tetrahydrofuran; water / 5 h / 25 °C
With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water;
|
|
Multi-step reaction with 2 steps
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 10 h / 20 °C
2: lithium hydroxide; water / tetrahydrofuran / 10 h
With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;
|
|
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
With piperidine; In N,N-dimethyl-formamide;
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Further stages;
|
- 56-41-7,25191-17-7,18875-37-1
L-alanin
- 73724-40-0
(S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoate
- 87512-31-0
(S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl) amino)propanamido)propanoic acid
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; In ethanol; acetone;
|
|
With sodium hydrogencarbonate; In tetrahydrofuran; water; at 25 ℃; for 5h;
|
1.77 g |
With sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 20 ℃; for 16h;
|
|
With sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 20 ℃; for 16h;
|
|
With sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 20 ℃; for 16h;
|
87512-31-0 Upstream products
-
1948-31-8
di-L-alanine
-
82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
-
56-41-7
L-alanin
-
73724-40-0
(S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoate
87512-31-0 Downstream products
-
697805-40-6
C51H58FN7O10
-
1438853-39-4
Nα-Fmoc-Ala-Ala-Asn(N-trityl)-PABC-PNP
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