53267-93-9
- Product Name：Boc-O-methyl-L-tyrosine
- Molecular Formula：C15H21NO5
- Purity：99%
- Molecular Weight：295.335
Product Details;
CAS#： 53267-93-9
Molecular Formula： C15H21NO5
Reputable Manufacturer Supply Best Quality 53267-93-9 with Fast Shipping
- Molecular Formula:C15H21NO5
- Molecular Weight:295.335
- Vapor Pressure:2.47E-09mmHg at 25°C
- Refractive Index:1.522
- Boiling Point:462 °C at 760 mmHg
- PKA:3.00±0.10(Predicted)
- Flash Point:233.2 °C
- PSA：84.86000
- Density:1.168 g/cm3
- LogP:2.60650
Boc-O-methyl-L-tyrosine(Cas 53267-93-9) Usage
InChI:InChI=1/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)9-10-5-7-11(20-4)8-6-10/h5-8,12H,9H2,1-4H3,(H,16,19)(H,17,18)/t12-/m0/s1
53267-93-9 Relevant articles
INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS
-
Paragraph 00250, (2021/11/06)
Provided herein are compounds that modul...
Design and synthesis of tripeptidyl furylketones as selective inhibitors against the β5 subunit of human 20S proteasome
Lü, Zirui,Li, Xiaona,Niu, Yan,Sun, Qi,Wang, Chao,Xi, Dandan,Xu, Fengrong,Xu, Ping,Zhou, Tongliang
, (2020/03/10)
A series of tripeptidic proteasome inhib...
EPHA4 CYCLIC PEPTIDE ANTAGONISTS AND METHODS OF USE THEREOF
-
Paragraph 0645-0646; 0648, (2019/11/19)
Disclosed herein are compounds and metho...
Design, synthesis and preliminary bioactivity studies of indomethacin derivatives as Bcl-2/Mcl-1 dual inhibitors
Chen, Chen,Nie, Yiming,Xu, Guangsen,Yang, Xinying,Fang, Hao,Hou, Xuben
, p. 2771 - 2783 (2019/05/15)
Bcl-2 family proteins, which divides int...
53267-93-9 Process route
-
- 94790-24-6
(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate
-
- 53267-93-9
O-methyl-N-tert-butoxycarbonyl-L-tyrosine
| Conditions | Yield |
|---|---|
|
With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 0 ℃; for 1h;
|
98% |
|
With sodium hydroxide; In methanol; water; at 20 ℃;
|
95% |
|
With sodium hydroxide; In methanol; water; at 20 ℃;
|
95% |
|
With sodium hydroxide; In 1,4-dioxane; at 24 ℃; for 2h;
|
84% |
|
With sodium hydroxide; In methanol; water; for 0.5h; Yield given;
|
|
|
(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate; With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h; pH=12 - 13;
With hydrogenchloride; In tetrahydrofuran; water; pH=2 - 3;
|
|
|
With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 0 ℃; for 1h;
|
|
|
With lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h;
|
-
- 3978-80-1
Boc-Tyr-OH
-
- 77-78-1
dimethyl sulfate
-
- 53267-93-9
O-methyl-N-tert-butoxycarbonyl-L-tyrosine
| Conditions | Yield |
|---|---|
|
With sodium hydroxide; at 20 - 30 ℃; Inert atmosphere;
|
95% |
|
Boc-Tyr-OH; With sodium hydroxide; In acetone; at 20 - 35 ℃; for 2h;
dimethyl sulfate; In water; acetone; at 0 - 50 ℃;
|
64% |
|
With sodium hydroxide;
|
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-
94790-24-6
(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate
53267-93-9 Downstream products
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