73731-37-0
- Product Name：2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
- Molecular Formula：C19H19NO5
- Purity：99%
- Molecular Weight：341.364
Product Details;
CAS#： 73731-37-0
Molecular Formula： C19H19NO5
Appearance： White to off-white crystalline powder
Quality Manufacturer Supply Best Quality 73731-37-0 with Reasonable Price
- Molecular Formula:C19H19NO5
- Molecular Weight:341.364
- Appearance/Colour:White to off-white crystalline powder
- Vapor Pressure:4.45E-15mmHg at 25°C
- Melting Point:115°C (dec.)
- Refractive Index:-15.5 ° (C=1, DMF)
- Boiling Point:596.5 °C at 760 mmHg
- PKA:3.49±0.10(Predicted)
- Flash Point:314.6 °C
- PSA：95.86000
- Density:1.327 g/cm3
- LogP:2.75000
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid(Cas 73731-37-0) Usage
InChI:InChI=1/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11-,17+/m1/s1
73731-37-0 Relevant articles
Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety
Zhu, Lunan,Zhu, Junchen,Sun, Xiaotong,Wu, Yaling,Wang, Huiying,Cheng, Lingping,Shen, Jiawei,Ke, Yanxiong
, p. 1080 - 1090 (2020/05/25)
Novel chiral selectors based on 3,5-dime...
General Fmoc-Based Solid-Phase Synthesis of Complex Depsipeptides Circumventing Problematic Fmoc Removal
Lobo-Ruiz, Ariadna,Tulla-Puche, Judit
supporting information, p. 183 - 192 (2020/01/24)
Development of an Fmoc-based solid-phase...
A Threonine-Forming Oxazetidine Amino Acid for the Chemical Synthesis of Proteins through KAHA Ligation
Baldauf, Simon,Schauenburg, Dominik,Bode, Jeffrey W.
supporting information, p. 12599 - 12603 (2019/08/01)
α-Ketoacid-hydroxylamine (KAHA) ligation...
Synthetic MUC1 antitumor vaccine with incorporated 2,3-sialyl-T carbohydrate antigen inducing strong immune responses with isotype specificity
Stra?burger, David,Glaffig, Markus,Stergiou, Natascha,Bialas, Sabrina,Besenius, Pol,Schmitt, Edgar,Kunz, Horst
, p. 1142 - 1146 (2018/10/21)
The endothelial glycoprotein MUC1 is kno...
73731-37-0 Process route
-
- 72-19-5,134357-96-3,7013-32-3,82822-12-6
L-threonine
-
- 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
-
- 73731-37-0
Fmoc-Thr-OH
| Conditions | Yield |
|---|---|
|
With sodium hydrogencarbonate;
|
100% |
|
L-threonine; N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium carbonate; In 1,4-dioxane; water; at 20 ℃; Inert atmosphere;
With hydrogenchloride; In water; pH=4;
|
100% |
|
With sodium hydrogencarbonate; In acetone;
|
97% |
|
With sodium carbonate; In 1,4-dioxane; at 0 ℃; for 24h;
|
94% |
|
L-threonine; With water; sodium carbonate; In 1,4-dioxane; Cooling with ice;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; In 1,4-dioxane; at 20 ℃; Cooling with ice;
With citric acid; In water; pH=3.5;
|
89% |
|
L-threonine; With N-cyclohexyl-cyclohexanamine; In acetone; at 20 ℃;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium carbonate; In water; acetonitrile; at 0 - 20 ℃; pH=8;
With potassium hydrogensulfate; In water; acetonitrile; pH=2 - 3;
|
58% |
|
With sodium hydrogencarbonate; In water; acetone;
|
-
- 72-19-5,134357-96-3,7013-32-3,82822-12-6
L-threonine
-
-
Carbonic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester 9H-fluoren-9-ylmethyl ester
-
- 73731-37-0
Fmoc-Thr-OH
| Conditions | Yield |
|---|---|
|
With potassium carbonate; In acetonitrile; at 20 ℃; for 2h;
|
80% |
73731-37-0 Upstream products
-
72-19-5
L-threonine
-
82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
-
88744-04-1
(9-fluorenyl)methyl pentafluorophenyl carbonate
-
133180-01-5
Fmoc-O-trityl-l-threonine
73731-37-0 Downstream products
-
150672-50-7
(2S,3R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butyric acid 3-methyl-oxetan-3-ylmethyl ester
-
98694-94-1
(2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butyric acid benzhydryl ester
-
86061-06-5
Nα-(9-fluorenylmethoxycarbonyl)-L-threonine pentafluorophenyl ester
-
89025-00-3
ester p-nitrophenolique de la N-(fluorenylmethyloxycarbonyl)-L-threonine
Relevant Products
-
Fmoc-L-Ala-OH·H2OCAS：207291-76-7
-
Fmoc-L-SerineCAS：73724-45-5
-
N-(tert-Butoxycarbonyl)-L-glutamineCAS：13726-85-7
