146982-27-6

  • Product Name:FMOC-LYS(ALOC)-OH
  • Molecular Formula:C25H28N2O6
  • Purity:99%
  • Molecular Weight:452.507
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Product Details;

CAS#: 146982-27-6

Molecular Formula: C25H28N2O6

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  • Molecular Formula:C25H28N2O6
  • Molecular Weight:452.507
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:87-91oC 
  • Refractive Index:1.579 
  • Boiling Point:689.699 ºC at 760 mmHg 
  • PKA:3.88±0.21(Predicted) 
  • Flash Point:370.917 ºC 
  • PSA:113.96000 
  • Density:1.237 g/cm3 
  • LogP:4.84260 

FMOC-LYS(ALOC)-OH(Cas 146982-27-6) Usage

InChI:InChI=1/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1

146982-27-6 Relevant articles

A procedure for the large scale preparation of N(ε)-Alloc-lysine and N(ε)-Alloc-N(α)-Fmoc-lysine

Crivici,Lajoie

, p. 49 - 53 (1993)

This report describes a convenient proce...

Cyclization of peptides through a urea bond: Application to the Arg-Gly-Asp tripeptide

Schmidt, Julien,Garambois, Veronique,Rocheblave, Luc,Martinez, Jean,Pelegrin, Andre,Cavelier, Florine,Vives, Eric

, p. 1083 - 1092 (2010)

Various synthetic cyclopeptides bind dif...

New effector conjugates, process for their production and their pharmaceutical use

-

Page/Page column 15, (2008/06/13)

Conjugates of epothilones and epothilone...

Allyl side chain protection in peptide synthesis

-

, (2008/06/13)

A system for the protection of amino aci...

146982-27-6 Process route

Fmoc-Lys-OH
105047-45-8

Fmoc-Lys-OH

Allyl chloroformate
2937-50-0

Allyl chloroformate

(S)-6-allyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid
146982-27-6

(S)-6-allyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid

Conditions
Conditions Yield
Fmoc-Lys-OH; Allyl chloroformate; With potassium carbonate; In 1,4-dioxane; water; at 23 ℃; for 20h;
With hydrogenchloride; In water;
94%
With sodium carbonate; In 1,4-dioxane; water; at 0 - 20 ℃;
 
9-fluorenylmethyl N-succinimidyl carbonate
102774-86-7

9-fluorenylmethyl N-succinimidyl carbonate

N<sup>Ε</sup>-allyloxycarbonyl-L-lysine hydrochloride
147529-99-5

NΕ-allyloxycarbonyl-L-lysine hydrochloride

(S)-6-allyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid
146982-27-6

(S)-6-allyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid

Conditions
Conditions Yield
With sodium carbonate; In 1,4-dioxane; for 18h; Yield given; Ambient temperature;
 

146982-27-6 Upstream products

  • 102774-86-7
    102774-86-7

    9-fluorenylmethyl N-succinimidyl carbonate

  • 147529-99-5
    147529-99-5

    NΕ-allyloxycarbonyl-L-lysine hydrochloride

  • 105047-45-8
    105047-45-8

    Fmoc-Lys-OH

  • 2937-50-0
    2937-50-0

    Allyl chloroformate

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