139262-23-0

  • Product Name:Nalpha-Fmoc-L-lysine hydrochloride
  • Molecular Formula:C21H25ClN2O4
  • Purity:99%
  • Molecular Weight:404.894
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Product Details;

CAS#: 139262-23-0

Molecular Formula: C21H25ClN2O4

Factory Supply Top Purity 139262-23-0 Customized Supply

  • Molecular Formula:C21H24N2O4*ClH
  • Molecular Weight:404.894
  • Vapor Pressure:1.29E-15mmHg at 25°C 
  • Refractive Index:-11.0 ° (C=1, DMF) 
  • Boiling Point:607.6 °C at 760 mmHg 
  • Flash Point:321.3 °C 
  • PSA:101.65000 
  • LogP:5.00050 

Nalpha-Fmoc-L-lysine hydrochloride(Cas 139262-23-0) Usage

InChI:InChI=1/C21H24N2O4.ClH/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18;/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25);1H/t19-;/m0./s1

139262-23-0 Relevant articles

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition

Belle, Roman,Al Temimi, Abbas H. K.,Kumar, Kiran,Pieters, Bas J. G. E.,Tumber, Anthony,Dunford, James E.,Johansson, Catrine,Oppermann, Udo,Brown, Tom,Schofield, Christopher J.,Hopkinson, Richard J.,Paton, Robert S.,Kawamura, Akane,Mecinovi?, Jasmin

supporting information, p. 13264 - 13267 (2017/12/26)

Histone lysine methylation is regulated ...

139262-23-0 Process route

Fmoc-D-Lys(BOC)-OH
92122-45-7

Fmoc-D-Lys(BOC)-OH

Fmoc-Lys-OH hydrochloride
201002-47-3,139262-23-0

Fmoc-Lys-OH hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; In diethyl ether; dichloromethane; for 16h;
 
9-fluorenylmethoxycarbonyl-L-alanine hydrochloride
139262-23-0

9-fluorenylmethoxycarbonyl-L-alanine hydrochloride

Ν<sub>ε</sub>-tert-butoxycarbonyl-Ν<sub>α</sub>-(9-fluorenylmethoxycarbonyl)-Ν<sub>ε</sub>-methyllysine
951695-85-5,2044709-77-3

Νε-tert-butoxycarbonyl-Να-(9-fluorenylmethoxycarbonyl)-Νε-methyllysine

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / methanol; tetrahydrofuran / 9 h / 0 - 20 °C
2: sodium cyanoborohydride / water; methanol / 10 h / 20 °C
3: hydrogenchloride / water; methanol / 1 h / 20 °C / pH 5 - 6
4: sodium hydrogencarbonate / water; tetrahydrofuran / 4 h / 20 °C
With hydrogenchloride; sodium cyanoborohydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; water;
 
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / methanol; tetrahydrofuran / 9 h / 0 - 20 °C
2: sodium tetrahydroborate / water; methanol / 8 h / 20 °C
3: hydrogenchloride / water; methanol / 1 h / 20 °C / pH 5 - 6
4: sodium hydrogencarbonate / water; tetrahydrofuran / 4 h / 20 °C
With hydrogenchloride; sodium tetrahydroborate; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; water;
 
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / methanol; tetrahydrofuran / 9 h / 0 - 20 °C
2: sodium cyanoborohydride / water; methanol / 8 h / 20 °C
3: hydrogenchloride / water; methanol / 1 h / 20 °C / pH 5 - 6
4: sodium hydrogencarbonate / water; tetrahydrofuran / 4 h / 20 °C
With hydrogenchloride; sodium cyanoborohydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; water;
 

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