1159680-21-3
- Product Name：L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- Molecular Formula：C35H42N4O7S
- Purity：99%
- Molecular Weight：662.807
Product Details;
CAS#： 1159680-21-3
Molecular Formula： C35H42N4O7S
Factory Supply Best Quality 1159680-21-3 In Bulk Supply
- Molecular Formula:C35H42N4O7S
- Molecular Weight:662.807
- PKA:3.87±0.21(Predicted)
- PSA：175.29000
- Density:1.35±0.1 g/cm3(Predicted)
- LogP:7.64340
1159680-21-3 Relevant articles
Preparation method of eptifibatide key raw material L-higher arginine
-
Paragraph 0041-0044, (2021/02/20)
The invention discloses a preparation me...
1159680-21-3 Process route
-
-
Fmoc-L-arginine hydrochloride
-
- 154445-78-0
2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl chloride
-
- 1159680-21-3
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)hexanoic acid
| Conditions | Yield |
|---|---|
|
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In water; acetone; at 20 - 25 ℃; for 3h; pH=7 - 7.5;
|
81.3% |
-
- 71989-26-9
Fmoc-Lys(tert-butoxycarbonyl)
-
- 1159680-21-3
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)hexanoic acid
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 4 steps
1: hydrogenchloride / N,N-dimethyl-formamide; water / 2 h / 20 - 25 °C
2: triethylamine / N,N-dimethyl-formamide / 6 h / 20 - 25 °C / Industrial scale
3: hydrogenchloride / water; ethyl acetate / 2 h / 0 - 25 °C
4: N-ethyl-N,N-diisopropylamine; sodium hydrogencarbonate / water; acetone / 3 h / 20 - 25 °C / pH 7 - 7.5
With hydrogenchloride; sodium hydrogencarbonate; triethylamine; N-ethyl-N,N-diisopropylamine; In water; ethyl acetate; N,N-dimethyl-formamide; acetone;
|
1159680-21-3 Upstream products
-
154445-78-0
2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl chloride
-
71989-26-9
Fmoc-Lys(tert-butoxycarbonyl)
-
139262-23-0
9-fluorenylmethoxycarbonyl-L-alanine hydrochloride
1159680-21-3 Downstream products
-
1245276-06-5
H-Ala-NVal-Aib-Glu-Ile-Gln-Leu-Nle-His-Gln-Har-NH2
-
1245276-08-7
H-Aib-Val-Aib-Glu-Ile-Gln-Leu-NNle-His-Gln-Har-NH2
-
1337909-13-3
Ac-D-Cha-L-Aze-D-Tyr-L-hArg-NH2
-
725272-96-8
Gu-Tx-D-Cha-L-Aze-D-Tyr-L-hArg-NH2
Relevant Products
-
FMOC-Arg(Pbf)-OHCAS：154445-77-9
-
FMOC-D-CIT-OHCAS：200344-33-8
-
Fmoc-l-homoarg(et)2-oh hydrochloride saltCAS：1864003-26-8
