94744-50-0

  • Product Name:Fmoc-Aib-OH
  • Molecular Formula:C19H19NO4
  • Purity:99%
  • Molecular Weight:325.364
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Product Details;

CAS#: 94744-50-0

Molecular Formula: C19H19NO4

Chinese Factory Supply 94744-50-0 with Efficient Transportation, Buy Quality Fmoc-Aib-OH

  • Molecular Formula:C19H19NO4
  • Molecular Weight:325.364
  • Melting Point:182-188 °C 
  • Refractive Index:1.614 
  • Boiling Point:544.3 °C at 760 mmHg 
  • PKA:3.98±0.10(Predicted) 
  • Flash Point:283 °C 
  • PSA:75.63000 
  • Density:1.256 g/cm3 
  • LogP:3.77920 

Fmoc-Aib-OH(Cas 94744-50-0) Usage

InChI:InChI=1/C19H19NO4/c1-19(20,18(22)23)10-17(21)24-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16H,10-11,20H2,1H3,(H,22,23)

94744-50-0 Relevant articles

Radical-Mediated Activation of Esters with a Copper/Selectfluor System: Synthesis of Bulky Amides and Peptides

Matsumoto, Akira,Wang, Zhe,Maruoka, Keiji

, p. 5401 - 5411 (2021/04/12)

Herein, we describe a new approach for t...

GLP-1 PRODRUGS

-

Page/Page column, (2015/02/25)

The invention relates to a GLP-1 prodrug...

A one-pot procedure for the preparation of N-9-fluorenylmethyloxycarbonyl- α-amino diazoketones from α-amino acids

Siciliano, Carlo,De Marco, Rosaria,Guidi, Ludovica Evelin,Spinella, Mariagiovanna,Liguori, Angelo

, p. 10575 - 10582 (2013/02/22)

The study describes a new "one-pot" rout...

Exploiting an inherent neighboring group effect of α-amino acids to synthesize extremely hindered dipeptides

Brown, Zachary Z.,Schafmeister, Christian E.

supporting information; experimental part, p. 14382 - 14383 (2009/02/08)

The creation of highly hindered peptides...

94744-50-0 Process route

(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

2-amino-2-methyl-propanoic acid hydrochloride
5938-34-1

2-amino-2-methyl-propanoic acid hydrochloride

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-α-aminoisobutyric acid
94744-50-0

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-α-aminoisobutyric acid

Conditions
Conditions Yield
With water; sodium carbonate; In 1,4-dioxane; for 16h;
83%
With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 2h;
 
2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-2-methyl-propionic acid <i>tert</i>-butyl ester

2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyl-propionic acid tert-butyl ester

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-α-aminoisobutyric acid
94744-50-0

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-α-aminoisobutyric acid

Conditions
Conditions Yield
With ytterbium(III) triflate; In nitromethane; at 45 - 50 ℃; for 5h;
97%

94744-50-0 Upstream products

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    2-Aminoisobutyric acid

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    1,1,1,3',3',3'-hexafluoro-propanol

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    Fmoc-Aib-SA

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