68858-20-8
- Product Name：Fmoc-L-Valine
- Molecular Formula：C20H21NO4
- Purity：99%
- Molecular Weight：339.391
Product Details;
CAS#： 68858-20-8
Molecular Formula： C20H21NO4
Appearance： white to light yellow crystal powder
Factory Supply High Purity ≥99.5% Pure 68858-20-8 with Fast Shipping
- Molecular Formula:C20H21NO4
- Molecular Weight:339.391
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:5.19E-13mmHg at 25°C
- Melting Point:143-145 °C(lit.)
- Refractive Index:-17.5 ° (C=1, DMF)
- Boiling Point:551.8 °C at 760 mmHg
- PKA:3.90±0.10(Predicted)
- Flash Point:287.5 °C
- PSA：79.12000
- Density:1.229 g/cm3
- LogP:3.83870
Fmoc-L-Valine(Cas 68858-20-8) Usage
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General Description |
The product number for this product was previously 04-12-1039.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
InChI:InChI=1/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/p-1/t18-/m0/s1
68858-20-8 Relevant articles
Self-assembly and anion-response of azobenzene-based L-valinamide derivative
Li, Kechang,Xue, Pengchong
, p. 206 - 212 (2018)
An azobenzene-based L-valinamide derivat...
Fungal Dioxygenase AsqJ Is Promiscuous and Bimodal: Substrate-Directed Formation of Quinolones versus Quinazolinones
Einsiedler, Manuel,Jamieson, Cooper S.,Maskeri, Mark A.,Houk, Kendall N.,Gulder, Tobias A. M.
supporting information, p. 8297 - 8302 (2021/03/01)
Previous studies showed that the FeII/α-...
Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety
Zhu, Lunan,Zhu, Junchen,Sun, Xiaotong,Wu, Yaling,Wang, Huiying,Cheng, Lingping,Shen, Jiawei,Ke, Yanxiong
, p. 1080 - 1090 (2020/05/25)
Novel chiral selectors based on 3,5-dime...
COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS
-
Paragraph 0546; 0551-0552, (2020/02/06)
The present disclosure provides novel po...
Determination of Chemical and Enantiomeric Purity of α-Amino Acids and their Methyl Esters as N-Fluorenylmethoxycarbonyl Derivatives Using Amylose-derived Chiral Stationary Phases
Islam, Md. Fokhrul,Adhikari, Suraj,Paik, Man-Jeong,Lee, Wonjae
, p. 332 - 338 (2019/04/13)
Liquid chromatographic enantiomer separa...
68858-20-8 Process route
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- 126727-02-4
Fmoc-valine
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- 68858-20-8
Fmoc-Val-OH
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- 84624-17-9
N-(9-fluorenylmethoxycarbonyl)-D-valine
| Conditions | Yield |
|---|---|
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With trifluoroacetic acid; In hexane; isopropyl alcohol; at 25 ℃; Reagent/catalyst; Resolution of racemate;
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With chiral column based on 3,5-dimethylphenylcarbamoylated β-cyclodextrin combining cinchona alkaloid immobilized on silica gel; In methanol; formic acid; triethylamine; acetonitrile; at 25 ℃; enantioselective reaction; Resolution of racemate;
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- 516-06-3,25609-85-2,7004-03-7,921-10-8
D,L-valine
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- 68858-20-8
Fmoc-Val-OH
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- 84624-17-9
N-(9-fluorenylmethoxycarbonyl)-D-valine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1.1: sodium carbonate / water; 1,4-dioxane / Cooling with ice
1.2: 5 h / 20 °C
2.1: trifluoroacetic acid / isopropyl alcohol; hexane / 25 °C / Resolution of racemate
With sodium carbonate; trifluoroacetic acid; In 1,4-dioxane; hexane; water; isopropyl alcohol;
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68858-20-8 Upstream products
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72-18-4
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-
102774-86-7
9-fluorenylmethyl N-succinimidyl carbonate
-
100803-86-9
3-(9-Fluorenylmethoxycarbonyl)-benzothiazoline-2-thione
68858-20-8 Downstream products
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130878-68-1
2,5-dioxopyrrolidin-1-yl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valinate
-
84000-01-1
9H-fluoren-9-ylmethyl (S)-4-isopropyl-5-oxo-1,3-oxazolidine-3-carboxylate
-
113534-40-0
Fmoc-Val-OTDO
-
86060-87-9
Fmoc-Val-OPfp
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