71989-28-1
- Product Name：Fmoc-L-Methionine
- Molecular Formula：C20H21NO4S
- Purity：99%
- Molecular Weight：371.457
Product Details;
CAS#： 71989-28-1
Molecular Formula： C20H21NO4S
Appearance： white to light yellow crystal powder
Factory Supply High Purity Top Purity ≥99.5% 71989-28-1 with Safe Transportation
- Molecular Formula:C20H21NO4S
- Molecular Weight:371.457
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:5.8E-16mmHg at 25°C
- Melting Point:121-123 °C(lit.)
- Refractive Index:-29.5 ° (C=1, DMF)
- Boiling Point:614.6 °C at 760 mmHg
- PKA:3.72±0.10(Predicted)
- Flash Point:325.5 °C
- PSA：100.93000
- Density:1.282 g/cm3
- LogP:4.12230
Fmoc-L-Methionine(Cas 71989-28-1) Usage
InChI:InChI=1/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/p-1/t18-/m0/s1
71989-28-1 Relevant articles
Diethyl Selenodiglycolate: An Eco-Friendly Synthetic Antioxidant with Potential Application to Inflammatory Disorders
Archilha, Marcos V. L. R.,Giroldo, Lilian,Kuznetsov, Aleksey E.,Meotti, Flávia C.,Pinatto-Botelho, Marcos F.,da Silva, Railmara P.,dos Santos, Alcindo A.
, p. 1239 - 1248 (2020/10/14)
This study describes a single step, high...
Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety
Zhu, Lunan,Zhu, Junchen,Sun, Xiaotong,Wu, Yaling,Wang, Huiying,Cheng, Lingping,Shen, Jiawei,Ke, Yanxiong
, p. 1080 - 1090 (2020/05/25)
Novel chiral selectors based on 3,5-dime...
Repurposing the Pummerer Rearrangement: Determination of Methionine Sulfoxides in Peptides
Woodroofe, Carolyn C.,Ivanic, Joseph,Monti, Sarah,Levine, Rodney L.,Swenson, Rolf E.
, p. 508 - 516 (2019/11/13)
The reversible oxidation of methionine r...
Determination of Chemical and Enantiomeric Purity of α-Amino Acids and their Methyl Esters as N-Fluorenylmethoxycarbonyl Derivatives Using Amylose-derived Chiral Stationary Phases
Islam, Md. Fokhrul,Adhikari, Suraj,Paik, Man-Jeong,Lee, Wonjae
, p. 332 - 338 (2019/04/13)
Liquid chromatographic enantiomer separa...
71989-28-1 Process route
-
- 63-68-3,26062-47-5,58576-49-1
L-methionine
-
- 28920-43-6
(fluorenylmethoxy)carbonyl chloride
-
![N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine](/upload/2024/7/f905b1c2-40c9-4c6d-a724-e6d9d0d9fa47.png)
- 71989-28-1
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine
| Conditions | Yield |
|---|---|
|
L-methionine; With chloro-trimethyl-silane; In dichloromethane; for 1h; Inert atmosphere; Reflux;
(fluorenylmethoxy)carbonyl chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 5 - 20 ℃; for 1.5h;
|
80% |
|
In acetonitrile; at 20 ℃; for 0.25h; pH=9.2; aq. borate buffer;
|
|
|
L-methionine; With sodium carbonate; In 1,4-dioxane; water; Cooling with ice;
(fluorenylmethoxy)carbonyl chloride; In 1,4-dioxane; water; at 20 ℃; for 5h;
|
-
- 63-68-3,26062-47-5,58576-49-1
L-methionine
-
- 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
-
- 71989-28-1
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine
| Conditions | Yield |
|---|---|
|
With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 50 ℃;
|
78% |
|
L-methionine; With N-cyclohexyl-cyclohexanamine; In acetone; at 20 ℃;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium carbonate; In water; acetonitrile; at 0 - 20 ℃; pH=8;
With potassium hydrogensulfate; In water; acetonitrile; pH=2 - 3;
|
61% |
|
With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;
|
71989-28-1 Upstream products
-
63-68-3
L-methionine
-
88744-04-1
(9-fluorenyl)methyl pentafluorophenyl carbonate
-
500872-34-4
Fmoc-L-Met-OMe
-
5269-64-7
O-(Trimethylsilyl)methionine
71989-28-1 Downstream products
-
71989-29-2
Fmoc-Met-ONp
-
113534-32-0
Fmoc-Met-OTDO
-
2488-15-5
N-tert-butoxycarbonyl-L-methionine
-
86060-94-8
N-α-Fmoc-L-methionine pentafluorophenyl ester
Relevant Products
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FMOC-Arg(Pbf)-OHCAS：154445-77-9
-
N-alpha-FMOC-Nepsilon-BOC-L-LysineCAS：71989-26-9
-
FMOC-L-PhenylalanineCAS：35661-40-6
