35661-60-0

  • Product Name:Fmoc-L-Leucine
  • Molecular Formula:C21H23NO4
  • Purity:99%
  • Molecular Weight:353.418
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Product Details;

CAS#: 35661-60-0

Molecular Formula: C21H23NO4

Appearance: white to light yellow crystal powder

Trustworthy Factory Supply 35661-60-0 with Safe Shipping, Buy High Quality Fmoc-L-Leu-OH

  • Molecular Formula:C21H23NO4
  • Molecular Weight:353.418
  • Appearance/Colour:white to light yellow crystal powder 
  • Vapor Pressure:2.28E-13mmHg at 25°C 
  • Melting Point:152-156 °C(lit.) 
  • Refractive Index:-25 ° (C=1, DMF) 
  • Boiling Point:559.8 °C at 760 mmHg 
  • PKA:3.91±0.21(Predicted) 
  • Flash Point:292.4 °C 
  • PSA:75.63000 
  • Density:1.207 g/cm3 
  • LogP:4.41530 

Fmoc-L-Leucine(Cas 35661-60-0) Usage

Biological Activity

Anti-inflammatory agent; increases intracellular Ca 2+ levels.

Biochem/physiol Actions

PPARγ ligand that induces insulin sensitization, but not adipogenesis.

InChI:InChI=1/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/p-1/t19-/m1/s1

35661-60-0 Relevant articles

Fungal Dioxygenase AsqJ Is Promiscuous and Bimodal: Substrate-Directed Formation of Quinolones versus Quinazolinones

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The following were discovered: a cyclic ...

Novel chiral stationary phases based on 3,5-dimethyl phenylcarbamoylated β-cyclodextrin combining cinchona alkaloid moiety

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Novel chiral selectors based on 3,5-dime...

Unwanted hydrolysis or α/β-peptide bond formation: How long should the rate-limiting coupling step take?

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Nowadays, in Solid Phase Peptide Synthes...

35661-60-0 Process route

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Fmoc-Leu-OH
35661-60-0

Fmoc-Leu-OH

N-Fmoc-β-alanine
35737-10-1

N-Fmoc-β-alanine

9-Fluorenylmethanol
24324-17-2

9-Fluorenylmethanol

Conditions
Conditions Yield
With water; potassium carbonate; In acetonitrile; at 20 ℃; for 6h;
70 %Chromat.
10 %Chromat.
22 %Chromat.
(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
170642-24-7

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

pseudoephedrine
90-82-4,7009-81-6,90-83-5,6912-63-6

pseudoephedrine

N-(9-fluorenylmethoxycarbonyl)-D-leucine
35661-60-0,126727-03-5,114360-54-2

N-(9-fluorenylmethoxycarbonyl)-D-leucine

Conditions
Conditions Yield
With sodium hydroxide; sodium hydrogencarbonate; Yield given. Multistep reaction; 1.) reflux, 2.) 1.5 h;
 

35661-60-0 Upstream products

  • 61-90-5
    61-90-5

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    28920-43-6

    (fluorenylmethoxy)carbonyl chloride

  • 102774-86-7
    102774-86-7

    9-fluorenylmethyl N-succinimidyl carbonate

  • 88744-04-1
    88744-04-1

    (9-fluorenyl)methyl pentafluorophenyl carbonate

35661-60-0 Downstream products

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    71989-25-8

    Fmoc-Leu-ONp

  • 113534-30-8
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    Fmoc-Leu-OTDO

  • 17195-26-5
    17195-26-5

    Leu-Ala-Gly-Val

  • 139932-46-0
    139932-46-0

    phenyl 3-<(4'-Nα-9-fluorenylmethoxycarbonylleucyloxymethyl)-phenyl>-3-trimethylsilylpropanoylglycinate

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